A conserved folding nucleus sculpts the free energy landscape of bacterial and archaeal orthologs from a divergent TIM barrel family
R Jain, K Muneeruddin, J Anderson… - Proceedings of the …, 2021 - National Acad Sciences
… indole-3-glycerol phosphate synthase (IGPS) TIM barrel … for three thermophilic indole-3-glycerolphosphate
synthase (… correlations between the archaeal Sulfolobus solfataricus (SsIGPS) …
synthase (… correlations between the archaeal Sulfolobus solfataricus (SsIGPS) …
Loop dynamics and the evolution of enzyme activity
… of TIM-barrel fold enzymes … indole-3-glycerol phosphate synthase (IGPS or TrpC in Fig.
2, centre right), which catalyses the closure of the CdRP ring into indole-3-glycerol phosphate (…
2, centre right), which catalyses the closure of the CdRP ring into indole-3-glycerol phosphate (…